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VLS-1488 (KIF18A-IN-6)

Product Specifications

CAS Number

2914879-10-8

Synonyms

KIF18A-IN-6

Target

Kinesin

Applications

Cytoskeletal Signaling

Molecular Formula

C28H37N3O5S2

Additionnal Information

VLS-1488 (KIF18A-IN-6) is an oral inhibitor of KIF18A with an IC50 of 0.016 μM. KIF18A is a mitotic kinesin motor protein that localizes at the plus-end of kinetochore microtubule spindle fibers and is crucial for cell division in aneuploid cancer cells with high chromosomal instability (CIN) .

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