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BGB-3245 (Brimarafenib)

Product Specifications

CAS Number

1643326-82-2

Synonyms

Brimarafenib, Brimarafenibum

Target

Raf

Applications

MAPK

Molecular Formula

C24H17F3N4O4

Additionnal Information

BGB-3245 (Brimarafenib, Brimarafenibum) is an inhibitor of Raf kinase. BGB-3245 displays potent effects against different RAF isoforms, including BRAF Class I/II/III mutations, BRAF fusions, and heterodimerization with CRAF in preclinical models. It also exhibits antineoplastic effects.

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