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Sovleplenib

Product Specifications

CAS Number

1415792-84-5

Synonyms

HMPL-523

Target

Syk

Applications

Protein Tyrosine Kinase

Molecular Formula

C24H30N6O3S

Additionnal Information

Sovleplenib (HMPL-523) is a highly potent and selective SYK inhibitor with IC50 of 0.025 μM, that exhibits anti-tumor activities in vitro and in vivo. Sovleplenib exhibits synergistic activities in combination with BTK, PI3Kδ, and Bcl2 family inhibitors in killing human-diffused large B cell lymphoma (DLBCL) .
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