Trilaciclib dihydrochloride
Product Specifications
CAS Number
1977495-97-8
Synonyms
G1T28 dihydrochloride
Target
CDK
Applications
Cell Cycle
Molecular Formula
C24H30N8O.2ClH
Additionnal Information
Trilaciclib dihydrochloride (G1T28 dihydrochloride) is a potent inhibitor of CDK4/cyclin D1 and CDK6/cyclin D3 with IC50s of 1 nM and 4 nM for CDK4 and CDK6, respectively. Trilaciclib hydrochloride regulates cell proliferation and protects against chemotherapy toxicity in murine and canine bone marrow cells.
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