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Infigratinib Phosphate

Product Specifications

CAS Number

1310746-10-1

Synonyms

NVP-BGJ398 phosphate

Target

FGFR

Applications

Protein Tyrosine Kinase

Molecular Formula

C26H31Cl2N7O3.H3O4P

Additionnal Information

Infigratinib Phosphate (NVP-BGJ398 phosphate) is the phosphate salt form of infigratinib, an orally bioavailable pan-inhibitor of human fibroblast growth factor receptors (FGFRs) with IC50 of 0.9 nM, 1.4 nM, 1 nM, and 60 nM for FGFR1, FGFR2, FGFR3, and FGFR4 respectively. It also has potential antiangiogenic, antineoplastic and antitumor activities.

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