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Poseltinib

Product Specifications

CAS Number

1353552-97-2

Synonyms

HM71224, LY3337641

Target

BTK

Applications

Protein Tyrosine Kinase

Smiles

CN1CCN (CC1) C2=CC=C (NC3=NC (=C4OC=CC4=N3) OC5=CC (=CC=C5) NC (=O) C=C) C=C2

Molecular Formula

C26H26N6O3

Additionnal Information

Poseltinib (HM71224, LY3337641) shows a highly selective inhibition for Bruton’s tyrosine kinase (BTK) with IC50 of 1.95 nM, in which the selectivity toward other BMX, TEC and TXK are 0.3, 2.3 and 2.4 fold, respectively.

Storage Conditions

3 years -20°C powder

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