Garcinone D
Product Specifications
CAS Number
107390-08-9
Target
STAT
Applications
Apoptosis
Molecular Formula
C24H28O7
Additionnal Information
Garcinone D is a natural xanthone from mangosteen, an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 with an IC50 of 28.23 μM. It promotes neural stem cell proliferation via STAT3 and Nrf2/HO-1 activation while inhibiting prostate and breast cancer growth by blocking the CDK2/CyclinE1-mediated cell cycle and can be used in prostate and breast cancer research.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
313073-01 50 µL
DBH (Dopamine beta-hydroxylase, Dopamine beta-Monooxygenase, Soluble dopamine beta-hydroxylase)
Sign In for Pricing
View Details 313073-02 100 µL
DBH (Dopamine beta-hydroxylase, Dopamine beta-Monooxygenase, Soluble dopamine beta-hydroxylase)
Sign In for Pricing
View Details MBS2161720-01 96 Tests
LIM And Senescent Cell Antigen Like Domains Protein 1 (LIMS1) Magnetic Fluorescence Assay Kit
Sign In for Pricing
View Details MBS2161720-02 5x 96 Tests
LIM And Senescent Cell Antigen Like Domains Protein 1 (LIMS1) Magnetic Fluorescence Assay Kit
Sign In for Pricing
View Details