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7-ketocholesterol

Product Specifications

CAS Number

566-28-9

Synonyms

7-Oxocholesterol;5-Cholesten-3β-ol-7-one

Target

HMG-CoA Reductase

Applications

Metabolism

Molecular Formula

C27H44O2

Additionnal Information

7-Ketocholesterol (7-Oxocholesterol), is a bioactive sterol and prominent cholesterol oxidation product, is a strong inhibitor of HMG-CoA reductase and cytochrome P450 7A1. It enhances oxidative stress, endoplasmic reticulum stress, and apoptosis in macrophages.

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