7-ketocholesterol
Product Specifications
CAS Number
566-28-9
Synonyms
7-Oxocholesterol;5-Cholesten-3β-ol-7-one
Target
HMG-CoA Reductase
Applications
Metabolism
Molecular Formula
C27H44O2
Additionnal Information
7-Ketocholesterol (7-Oxocholesterol), is a bioactive sterol and prominent cholesterol oxidation product, is a strong inhibitor of HMG-CoA reductase and cytochrome P450 7A1. It enhances oxidative stress, endoplasmic reticulum stress, and apoptosis in macrophages.
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