Kira8
Product Specifications
CAS Number
1630086-20-2
Synonyms
Ire-1 inhibitor, AMG-18
Target
IRE1
Applications
ER stress & UPR
Smiles
CC1=C (OC2=C (C=CC=N2) C3=NC (=NC=C3) NC4CCCNC4) C5=C (C=C1) C (=CC=C5) N[S; v6] (=O) (=O) C6=C (Cl) C=CC=C6
Molecular Formula
C31H29ClN6O3S
Additionnal Information
Kira8 (Ire-1 inhibitor, AMG-18) is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.
Storage Conditions
3 years -20°C powder
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