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SKF-86002

Product Specifications

CAS Number

72873-74-6

Target

P38 MAPK

Applications

MAPK

Smiles

FC1=CC=C (C=C1) C2=C ([N]3CCSC3=N2) C4=CC=NC=C4

Molecular Formula

C16H12FN3S

Additionnal Information

SKF-86002 is an orally active p38 MAPK inhibitor, inhibits lipopolysaccharide (LPS) -stimulate human monocyte IL-1 and TNF-α production with IC50 of 1 μM, also inhibits lipoxygenase- and cyclooxygenase-mediated metabolism of arachidonic acid.

Storage Conditions

3 years -20°C powder

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