A-3 hydrochloride
Product Specifications
CAS Number
78957-85-4
Target
PKA
Applications
Stem Cells & Wnt
Smiles
Cl.NCCN[S] (=O) (=O) C1=C2C=CC=C (Cl) C2=CC=C1
Molecular Formula
C12H13ClN2O2S.ClH
Additionnal Information
A-3 hydrochloride, a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases, againsts cAMP-dependent protein kinase (PKA) (Ki=4.3 μM), casein kinase II (CK2) (Ki=5.1 μM) and myosin light chain kinase (MLCK) (Ki=7.4 μM), also inhibits Protein Kinase C (PKC) and casein kinase I (CK1) with Ki values of 47 μM and 80 μM, respectively.
Storage Conditions
3 years -20°C powder
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