SPP-86
Product Specifications
CAS Number
1357349-91-7
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CC (C) [N]1N=C (C#CC2=CC=CC=C2) C3=C (N) N=CN=C13
Molecular Formula
C16H15N5
Additionnal Information
SPP-86, a potent and selective cell permeable inhibitor of rearranged during transfection (RET) tyrosine kinase with an IC50 of 8 nM, inhibits RET-induced phosphatidylinositide 3-kinases (PI3K) /Akt and MAPK signaling, also inhibits RET-induced estrogen receptorα (ERα) phosphorylation in MCF7 cells.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
CWB50825-01 250 mg
1-Methyl-3- (pyridin-3-yl) -1H-pyrazole-4-carbaldehyde
Sign In for Pricing
View Details CWB50825-02 2.5 g
1-Methyl-3- (pyridin-3-yl) -1H-pyrazole-4-carbaldehyde
Sign In for Pricing
View Details 
NBP2-98492AF594 0.1 mL
Rabbit Polyclonal NUFIP1 Antibody [Alexa Fluor 594]
Sign In for Pricing
View Details