What is the catalog number for DBr-1?

The catalog number for DBr-1 is C02006-1g.

What sizes are available for DBr-1?

DBr-1 is available in the following size(s): 1 g.

DBr-1 is currently made to order / not held in immediate stock. Contact us for lead time.

DBr-1

Product Specifications

Target

Epigenetic Reader Domain

Applications

Epigenetics

Additionnal Information

DBr-1 is a DCAF1-BRD9 PROTAC, created by linking the BRD9 binder BI-956448 to the DCAF1 scaffold via a piperidine-aliphatic carbon linker. It is a potent and selective degrader of BRD9 with a DC50 of 90 nM. It overcomes intrinsic resistance to VHL-degraders, positioning DCAF1-PROTACs as a promising strategy to counter ligase-mediated resistance.