BAY-850
Product Specifications
CAS Number
2099142-76-2
Target
ATPase
Applications
Transmembrane Transporters
Smiles
O=C (N[C@H] (CC1=CC=C (C#N) C=C1) CN[C@H]2CC[C@@H] (N) CC2) C3=CC (C4=CC=C (CN[C@@H] (C5=CC=C (C) C=C5) C) O4) =C (OC) C=C3Cl
Molecular Formula
C38H44ClN5O3
Additionnal Information
BAY-850 is a potent and isoform-selective inhibitor of the ATPase family AAA domain-containing protein 2 (ATAD2) bromodomain, with an IC50 of 166 nM in TR-FRET assays. It induces ATAD2 bromodomain dimerization and effectively blocks its interaction with acetylated histones in vitro.
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