SOP1812
Product Specifications
CAS Number
2546091-70-5
Synonyms
QN-302
Target
Others
Applications
Others
Molecular Formula
C45H57N7O6
Additionnal Information
SOP1812 (QN-302), is a tetra-substituted naphthalene diimide (ND) derivative and selective inhibitor of G-quadruplex (G4) transcription. It shows great affinity to hTERT G4 and HuTel21 G4 with KD values of 4.9 and 28.4 nM, respectively. It binds to G-quadruplex DNA in cancer gene promoters region and shows strong anti-proliferative and anti-tumor activity in pancreatic cancer models.
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