Irpagratinib
Product Specifications
CAS Number
2230974-62-4
Synonyms
ABSK011
Target
FGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C28H32F2N6O5
Additionnal Information
Irpagratinib (ABSK011) is a potent inhibitor of FGFR4 with an IC50 of < 10 nM in biochemical assays. It effectively suppresses FGFR4 auto-phosphorylation and disrupts downstream signal transduction. It also strongly inhibits tumor growth and induces regression in subcutaneous xenograft models.
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