Irpagratinib
Product Specifications
CAS Number
2230974-62-4
Synonyms
ABSK011
Target
FGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C28H32F2N6O5
Additionnal Information
Irpagratinib (ABSK011) is a potent inhibitor of FGFR4 with an IC50 of < 10 nM in biochemical assays. It effectively suppresses FGFR4 auto-phosphorylation and disrupts downstream signal transduction. It also strongly inhibits tumor growth and induces regression in subcutaneous xenograft models.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PKSV030387-01 50 µg
Recombinant SARS-CoV-2 Spike S1 (D614G) (His Tag)
Sign In for Pricing
View Details PKSV030387-02 500 µg
Recombinant SARS-CoV-2 Spike S1 (D614G) (His Tag)
Sign In for Pricing
View Details 