R16
Product Specifications
CAS Number
6325-13-9
Synonyms
NSC29869, Nrf2-IN-3
Target
Nrf2
Applications
NF-κB
Molecular Formula
C22H26N4O4S
Additionnal Information
R16 (NSC29869, Nrf2-IN-3) is an inhibitor of NRF2 (nuclear factor erythroid 2-related factor 2) that selectively binds KEAP1 mutants and restores their NRF2-inhibitory function by repairing the disrupted KEAP1/NRF2 interactions. It significantly enhances the sensitivity of KEAP1-mutated tumor cells to cisplatin and gefitinib.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS205708-01 0.02 mg
TSSK6, 1-273aa, Human, His tag, E Coli (Denatured)
Sign In for Pricing
View Details MBS205708-02 0.1 mg
TSSK6, 1-273aa, Human, His tag, E Coli (Denatured)
Sign In for Pricing
View Details MBS205708-03 5x 0.02 mg
TSSK6, 1-273aa, Human, His tag, E Coli (Denatured)
Sign In for Pricing
View Details MBS205708-04 0.5 mg
TSSK6, 1-273aa, Human, His tag, E Coli (Denatured)
Sign In for Pricing
View Details MBS205708-05 5x 0.1 mg
TSSK6, 1-273aa, Human, His tag, E Coli (Denatured)
Sign In for Pricing
View Details MBS205708-06 5x 0.5 mg
TSSK6, 1-273aa, Human, His tag, E Coli (Denatured)
Sign In for Pricing
View Details