What is the catalog number for AZD8421?

The catalog number for AZD8421 is C01989-25mg.

What sizes are available for AZD8421?

AZD8421 is available in the following size(s): 25 mg.

AZD8421 is currently made to order / not held in immediate stock. Contact us for lead time.

AZD8421

Product Specifications

CAS Number

3047321-53-6

Target

CDK

Applications

Cell Cycle

Molecular Formula

C18H32N8O3S

Additionnal Information

AZD8421 is a potent and highly selective inhibitor of Cyclin-dependent Kinase 2 (CDK2), with an IC50 against CDK2 of 9nM with selectivity over CDK1, CDK4 and CDK6. It also exhibits an anti-proliferative effect, effectively inhibits Rb phosphorylation, and shows strong activity both as a monotherapy and in combination with CDK4/6 inhibitors in breast and ovarian cancer models.