BAL-0028
Product Specifications
CAS Number
2842012-69-3
Target
NLRP3
Applications
Immunology & Inflammation
Molecular Formula
C24H22FN3O2
Additionnal Information
BAL-0028 (Compound 3), which belongs to the indazole class is an inhibitor of NLRP3 activation with an IC50 value of 25 nM. BAL-0028 binds tightly to the NACHT domain of NLRP3, with KD values ranging from 104 to 123 nM. BAL-0028 also exhibits anti-inflammatory activity.
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