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BMS-986365

Product Specifications

CAS Number

2446928-30-7

Synonyms

CC-94676

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Molecular Formula

C41H45F3N8O5S

Additionnal Information

BMS-986365 (CC-94676) is a potent and selective, heterobifunctional ligand-directed degrader (LDD) and antagonist of androgen receptor (AR), that effectively targets both wildtype and mutant forms of the androgen receptor (AR) in the cytoplasm and nucleus. It rapidly degrades AR, suppresses AR signaling, and shows promising clinical activity in inhibiting tumor growth in patients with metastatic castration-resistant prostate cancer (mCRPC) .

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