What is the catalog number for Tunlametinib?

The catalog number for Tunlametinib is C01969-1g.

What sizes are available for Tunlametinib?

Tunlametinib is available in the following size(s): 1 g.

Is Tunlametinib in stock?

Tunlametinib is currently made to order / not held in immediate stock. Contact us for lead time.

Tunlametinib

Product Specifications

CAS Number

1801756-06-8

Synonyms

HL-085

Target

MEK

Applications

Protein Tyrosine Kinase

Molecular Formula

C16H12F2IN3O3S

Additionnal Information

Tunlametinib (HL-085) is a highly selective and oral inhibitor of MEK1/2 with an IC50 of 1.9 nM for MEK1, with the potential to treat RAS/RAF mutant cancers. It also induces cell cycle arrest at the G0/G1 phase and promotes apoptosis in a dose-dependent manner. It also exhibits antitumor activity in patients with advanced NRAS-mutant melanoma.