What is the catalog number for ART899?

The catalog number for ART899 is C01966-1g.

What sizes are available for ART899?

ART899 is available in the following size(s): 1 g.

ART899 is currently made to order / not held in immediate stock. Contact us for lead time.

ART899

Product Specifications

CAS Number

2607139-85-3

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Molecular Formula

C19H13ClD3F4N3O4

Additionnal Information

ART899, a derivative of ART558 is a potent, specific allosteric inhibitor of DNA polymerase theta (Polθ), specifically inhibits Polθ MMEJ activity with IC50 of 180 nM. It specifically radiosensitizes tumor cells and have a potent stand-alone antitumor effect in cancer cells.