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PT-179

Product Specifications

CAS Number

2924858-25-1

Target

E3 Ligase

Applications

Ubiquitin

Molecular Formula

C17H17N3O5

Additionnal Information

PT-179, an orthogonal Thalidomide derivative targets cereblon without causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.
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