PT-179
Product Specifications
CAS Number
2924858-25-1
Target
E3 Ligase
Applications
Ubiquitin
Molecular Formula
C17H17N3O5
Additionnal Information
PT-179, an orthogonal Thalidomide derivative targets cereblon without causing off-target degradation effects. PT-179 specifically binds CRBN, forms a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediates the degradation of the tagged protein.
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