LTGO-33
Product Specifications
CAS Number
2834106-06-6
Target
Sodium Channel
Applications
Transmembrane Transporters
Molecular Formula
C21H17F4N3O3S
Additionnal Information
LTGO-33 is a potent and selective inhibitor of voltage-gated sodium channel NaV1.8. LTGO-33, with its potency in the nanomolar range, selectively inhibits NaV1.8 over 600 times more than human NaV1.1-NaV1.7 and NaV1.9. Its inhibition is not dependent on the state of the channels and displays consistent potency against both closed and inactivated conformations. LTGO-33 holds promise for research in pain disorders.
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