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NRL-1049

Product Specifications

CAS Number

1973494-16-4

Synonyms

BA 1049

Target

ROCK

Applications

Cytoskeletal Signaling

Molecular Formula

C16H21N3O2S

Additionnal Information

NRL-1049 (BA 1049) is a small molecule selective inhibitor of ROCK2 with an IC50 of 0.59 μM. It exhibits potent efficacy in preserving the blood-brain barrier (BBB) and suppresses seizures after brain injury, and inhibits hemorrhagic transformation after ischemic stroke in mice.
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