DDO-2728
Product Specifications
CAS Number
3029515-97-4
Target
Others
Applications
Others
Molecular Formula
C28H17F3N4O7
Additionnal Information
DDO-2728 is a selective pyrazolopyrimidine-based inhibitor of ALKBH5 with an IC50 of 2.97 μM. It increases the levels of N6-methyladenosine (m6A) modifications in acute myeloid leukemia (AML) cells and exhibits antiproliferative activity in these cells. It also demonstrates anti-tumor efficacy in the MV4−11 xenograft model.
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