B102 (PARP/HDAC-IN-1)
Product Specifications
Synonyms
PARP/HDAC-IN-1
Target
PARP
Applications
DNA Damage/DNA Repair
Additionnal Information
B102 (PARP/HDAC-IN-1) is a dual inhibitor of PARP and HDAC, with IC50 of 19.01 nM, 2.13 nM, 1.69 μM, > 10 μM for PARP1, PARP2, HDAC1, HDAC6, respectively, in an enzymatic assay. It exhibits anti-proliferative and anti-tumor effects. It also induces DNA damage and apoptosis in vitro.
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