Nedometinib
Product Specifications
CAS Number
2252314-46-6
Synonyms
NFX-179
Target
MEK
Applications
Protein Tyrosine Kinase
Molecular Formula
C17H16FIN4O3
Additionnal Information
Nedometinib (NFX-179) is a highly specific and potent inhibitor of MEK1 with an IC50 of 135 nM. It also results in suppression of p-ERK levels and can be used in research and treatment of cutaneous neurofibromas (cNFs) associated with neurofibromatosis type 1 (NF1) .
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