Nedometinib
Product Specifications
CAS Number
2252314-46-6
Synonyms
NFX-179
Target
MEK
Applications
Protein Tyrosine Kinase
Molecular Formula
C17H16FIN4O3
Additionnal Information
Nedometinib (NFX-179) is a highly specific and potent inhibitor of MEK1 with an IC50 of 135 nM. It also results in suppression of p-ERK levels and can be used in research and treatment of cutaneous neurofibromas (cNFs) associated with neurofibromatosis type 1 (NF1) .
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS6451287-01 0.1 mL
NCR3 (Natural Cytotoxicity Triggering Receptor 3, 1C7, CD337, LY117, MALS, NKp30) (MaxLight 750)
Sign In for Pricing
View Details MBS6451287-02 5x 0.1 mL
NCR3 (Natural Cytotoxicity Triggering Receptor 3, 1C7, CD337, LY117, MALS, NKp30) (MaxLight 750)
Sign In for Pricing
View Details 
orb2432880 100 µL
Phospho-Cofilin (Ser3) Rabbit Polyclonal Antibody (APC-Cy5.5)
Sign In for Pricing
View Details 
R355-75a T-75 Flask
Proliferating Rat Aortic Smooth Muscle Cells (RAOSMC), adult
Sign In for Pricing
View Details orb964680 100 µL
Phospho-HSF1 (Ser326) Rabbit Polyclonal Antibody (AP)
Sign In for Pricing
View Details