What is the catalog number for PCO371?

The catalog number for PCO371 is C01931-5mg.

What sizes are available for PCO371?

PCO371 is available in the following size(s): 5 mg.

PCO371 is currently made to order / not held in immediate stock. Contact us for lead time.

PCO371

Product Specifications

CAS Number

1613373-33-3

Target

Others

Applications

Others

Molecular Formula

C29H32F3N5O6S

Additionnal Information

PCO371 is a nonpeptidyl, orally active agonist of Parathyroid hormone type 1 receptor (PTHR1) . It stimulates cAMP production in COS-7 cells with an EC50 of 2.4 μmol/L. It also acts as an osteoporosis drug and significantly enhances bone mineral density (BMD) and bone strength in the lumbar vertebrae of osteopenic ovariectomized (OVX) rats. It also restores normal serum calcium levels without increasing urinary calcium in hypocalcemic thyroparathyroidectomized (TPTX) rats.