THZ1
Product Specifications
CAS Number
1604810-83-4
Target
CDK
Applications
Cell Cycle
Molecular Formula
C31H28ClN7O2
Additionnal Information
THZ1 is a potent and covalent inhibitor of CDK7 with an IC50 of 3.2 nM. It also inhibits the CDK12 and CDK13 and downregulates MYC expression. It exhibits strong anti proliferative effect across a broad range of cancer cell lines including human T-cell acute lymphoblastic leukaemia (T-ALL) cancer.
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