Pebezertinib
Product Specifications
CAS Number
2769954-39-2
Synonyms
LNG-451
Target
EGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C24H19F4N7O
Additionnal Information
Pebezertinib is a central nervous system (CNS) -penetrant, wild-type EGFR-sparing, covalent inhibitor of epidermal growth factor receptor (EGFR) exon 20 insertion (Ex20ins) with an IC50 of 7-78 nM. It also exhibits a potent anti-tumor efficacy.
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