GTS-21 dihydrochloride
Product Specifications
CAS Number
156223-05-1
Synonyms
DMXB-A, DMBX-anabaseine
Target
AChR
Applications
Neuronal Signaling
Molecular Formula
C19H20N2O2.2ClH
Additionnal Information
GTS-21 dihydrochloride (DMXB-A, DMBX-anabaseine) is a selective agonist of alpha7 nicotinic acetylcholine receptor (α7-nAChR) and exhibits anti‐inflammatory and cognition‐enhancing activities. GTS-21 dihydrochloride is also an antagonist of α4β2 with a Ki value of 20 nM for humanα4β2 and 5-HT3A receptor with an IC50 value of 3.1 μM.
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