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GTS-21 dihydrochloride

Product Specifications

CAS Number

156223-05-1

Synonyms

DMXB-A, DMBX-anabaseine

Target

AChR

Applications

Neuronal Signaling

Molecular Formula

C19H20N2O2.2ClH

Additionnal Information

GTS-21 dihydrochloride (DMXB-A, DMBX-anabaseine) is a selective agonist of alpha7 nicotinic acetylcholine receptor (α7-nAChR) and exhibits anti‐inflammatory and cognition‐enhancing activities. GTS-21 dihydrochloride is also an antagonist of α4β2 with a Ki value of 20 nM for humanα4β2 and 5-HT3A receptor with an IC50 value of 3.1 μM.

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