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TNG-462

Product Specifications

CAS Number

2760483-96-1

Target

PRMT

Applications

Epigenetics

Molecular Formula

C28H36N6O2S

Additionnal Information

TNG-462 is an orally active, potent and selective inhibitor of methylthioadenosine (MTA) -cooperative PRMT5. It exhibits significant antitumor activity, including durable regressions and complete responses, against methylthioadenosine phosphorylase (MTAP) deficiency and/or methylthioadenosine (MTA) accumulation solid tumors.

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