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GBD-9

Product Specifications

CAS Number

2864408-92-2

Target

E3 Ligase

Applications

Ubiquitin

Molecular Formula

C44H47N9O6

Additionnal Information

GBD-9 is a double-mechanism efficient degrader of BTK and GSPT1 by recruiting the E3 ligase cereblon (CRBN) . GBD-9 acts both as a PROTAC molecule to induce the degradation of BTK and as a molecular glue to degrade GSPT1.It exhibits anti-proliferative effects, inhibiting cancer cell survival.
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