GBD-9
Product Specifications
CAS Number
2864408-92-2
Target
E3 Ligase
Applications
Ubiquitin
Molecular Formula
C44H47N9O6
Additionnal Information
GBD-9 is a double-mechanism efficient degrader of BTK and GSPT1 by recruiting the E3 ligase cereblon (CRBN) . GBD-9 acts both as a PROTAC molecule to induce the degradation of BTK and as a molecular glue to degrade GSPT1.It exhibits anti-proliferative effects, inhibiting cancer cell survival.
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