ZK53
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Target
Others
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Additionnal Information
ZK53 is a selective activator of mitochondrial caseinolytic protease P (HsClpP) . It exhibits an EC50 of 1.37 μM for α-casein hydrolysis by HsClpP. ZK53 treatment allosterically activates HsClpP to uncontrollably degrade the essential mitochondrial proteins and is inactive toward bacterial ClpP proteins.
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