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Asundexian

Product Specifications

CAS Number

2064121-65-7

Synonyms

BAY-2433334

Target

Factor Xa

Applications

Metabolism

Smiles

COC (C (C1=C (N2C=C (N=N2) C (F) (F) F) C=CC (Cl) =C1) =C3) =CN ([C@@H] (CC) C (NC4=CC (F) =C (C=C4) C (N) =O) =O) C3=O

Molecular Formula

C26H21ClF4N6O4

Additionnal Information

Asundexian (BAY 2433334) is an orally administered inhibitor of coagulation factor XIa (FXIa) . It binds reversibly to the FXIa active site with high affinity, blocking its enzymatic function. In buffer systems, asundexian exhibits an IC50 of 1 nM against human FXIa.

Storage Conditions

3 years-20°C powder 2 years-80°C in solvent

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