Limertinib
Product Specifications
CAS Number
1934259-00-3
Synonyms
ASK120067
Target
EGFR
Applications
Protein Tyrosine Kinase
Molecular Formula
C29H32ClN7O2
Additionnal Information
Limertinib (ASK120067) is an irreversible third-generation inhibitor of EGFRT790M with IC50 of 0.3 nM, with selectivity over EGFRWT having IC50 of 6.0 nM. It exhibits potent anti-proliferation activity in non-small cell lung cancer (NSCLC) tumor cells.
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