What is the catalog number for Mepazine hydrochloride?

The catalog number for Mepazine hydrochloride is C01838-100mg.

What sizes are available for Mepazine hydrochloride?

Mepazine hydrochloride is available in the following size(s): 100 mg.

Is Mepazine hydrochloride in stock?

Mepazine hydrochloride is currently made to order / not held in immediate stock. Contact us for lead time.

Mepazine hydrochloride

Product Specifications

CAS Number

2975-36-2

Synonyms

Pecazine hydrochloride

Target

MALT

Applications

NF-κB

Molecular Formula

C19H22N2S.ClH

Additionnal Information

Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective inhibitor of MALT1 protease, with IC50 values of 0.83 μM for GSTMALT1 full length and 0.42 μM for GSTMALT1 aa 325-760. It effectively suppresses the activation of the NF-kB pathway specifically in activated B cell subtype of diffuse large B cell lymphoma (ABC-DLBCL) cells and makes it a promising candidate for the treatment of ABC-DLBCL.