PK11007
Product Specifications
CAS Number
874146-69-7
Target
P53
Applications
Apoptosis
Molecular Formula
C15H11ClFN5O3S2
Additionnal Information
PK11007 is a thiol-reactive anticancer agent that stabilizes p53 via selective alkylation of two surface cysteines without compromising its DNA binding. It induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels.
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