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PBIT

Product Specifications

CAS Number

2514-30-9

Target

Histone Demethylase

Applications

Epigenetics

Molecular Formula

C14H11NOS

Additionnal Information

PBIT is a specific inhibitor of the Jumonji AT-rich Interactive Domain 1 (JARID1) enzymes. It inhibits JARID1B (KDM5B/PLU1), JARID1Aand JARID1C with an IC50 of 3 μM, 6 μM and 4.9 μM respectively. It is capable of inhibiting the multiplication of breast cancer cell lines expressing high levels of JARIDB1.
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