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JW74

Product Specifications

CAS Number

863405-60-1

Target

Wnt/beta-catenin

Applications

Cytoskeletal Signaling

Molecular Formula

C24H20N6O2S

Additionnal Information

JW74 is a specific inhibitor of the canonical Wnt signaling with IC50 790 nM in the ST-Luc assay. It inhibit the growth of tumor cells in both mouse xenograft model of colorectal cancer and in ApcMin mice.

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