Senexin B
Product Specifications
CAS Number
1449228-40-3
Synonyms
SNX2-1-165, BCD-115
Target
CDK
Applications
Cell Cycle
Molecular Formula
C27H26N6O
Additionnal Information
Senexin B (SNX2-1-165, BCD-115) is a potent and selective small-molecule inhibitor of CDK8/19, with Kd values of 140 nM for CDK8 and 80 nM for CDK19. It significantly slows tumor growth and inhibits Triple-Negative Breast Cancer (TNBC) xenograft tumor progression.
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