CRT-0105446
Product Specifications
CAS Number
1661846-05-4
Target
LIM kinase
Applications
Cell Cycle
Molecular Formula
C20H18F3N3O2S
Additionnal Information
CRT 0105446 (compound 22d) is a potent inhibitor of LIMK1 with an IC50 of 8 nM. It can inhibit the growth of MCF-7 breast cancer cells and the invasion of MDA-MB-231 cells by reducing the expression of phosphorylated cofilin.
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