FL118
Product Specifications
CAS Number
135415-73-5
Synonyms
10,11- (Methylenedioxy) -20 (S) -camptothecin
Target
Survivin
Applications
Apoptosis
Molecular Formula
C21H16N2O6
Additionnal Information
FL118 (10,11- (Methylenedioxy) -20 (S) -camptothecin), a Camptothecin analog, is a potent and orally active inhibitor of Survivin. FL118 also selectively and independently inhibits three additional cancer-associated survival genes Mcl-1, XIAP, and cIAP2 in a p53 status-independent manner. FL118 displays potent antitumor activity and can be used in cancer research.
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